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Preclinical studies on a bioelectronic therapy of pulmonary arterial hypertension

June 5, 2018

Now that’s a plan with heart.  Great work Stavros Zanos, Chad Bouton, Timir Datta, Loren Rieth, Theodoros Zanos, Christopher Czura, Lance Becker, Yousef Al-Abed, Kevin King, Jacquelyn Tamaio, Todd Levy, Umair Ahmed, Khaled Qanud, United Therapeutics and anyone I missed.  All heart, y’all!

Posted by Stavros Zanos, Assistant Professor at the Feinstein Institute for Medical Research: “I am happy to announce that over the next few years, the Center for Bioelectronic Medicine and the Translational Neurophysiology lab at the Feinstein Institute will conduct a series of preclinical studies on a bioelectronic therapy of pulmonary arterial hypertension (PAH). PAH is characterized by increased resistance in the pulmonary vessels, which may progress to heart failure and death. We will test whether vagus nerve stimulation with the appropriate device, electrode, electrode placement and stimulation parameters can selectively produce vasodilation in the pulmonary circulation, relieve symptoms and delay the progression of the disease. The members of the research team are Khaled Qanud, Jacquelyn N. Tomaio, Umair Ahmed, with engineering support from Kevin King and Todd Levy. Collaborators in this project include the Cardiopulmonary Resuscitation Lab (Becker Lance), the Bioelectronics & Biosensors Lab (Timir Datta), the Microfabrication Lab (Loren Rieth) and the Neural Decoding lab (Theodoros Zanos). The program is supported by a generous research grant from United Therapeutics Corporation. Leadership team: Christopher J. Czura, PhD, Chad Bouton, Yousef Al-Abed, Becker Lance. More info: http://TNPLab.org/

#PulmonaryArterialHypertension #VagusNerve #Preclinical #Device #Electrode #Neurophysiology #heartfailure

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